BST1, Recombinant, Human, aa33-293, His-Tag (BST1, CD157, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2)

Catalog No : USB-470218
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Product name BST1, Recombinant, Human, aa33-293, His-Tag (BST1, CD157, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2)
Catalog No USB-470218
Supplier’s Catalog No 470218
Supplier US Biologicals
Source antigen Recombinant, Insect Cell
Reactivity
Cross reactivity
Applications
Molecular weight 30.5284
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description BST1, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, is a glycosylphosphatidyl inositol (GPI) anchored membrane protein that belongs to the CD38 family. It was originally identified as a bone marrow stromal cell molecule. This protein is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. Along with CD38, it exhibits both DP-ribosyl cyclase and cyclinc ADP ribose hydrolase activities. It may play a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines. Also, it is expressed by cells of the myeloid lineage and could act as a receptor with signal transduction capability. Recombinant human BST1, fused to His-Tag at C-terminal, expressed in Insect Cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa33-293 from human BST1, fused to His-Tag at C-terminal, expressed in Insect Cell. Molecular Weight: ~30.5kD (267aa) ~28-40kD (SDS-PAGE under reducing conditions) AA Sequence: RWRGEGTSAH LRDIFLGRCA EYRALLSPEQ RNKNCTAIWE AFKVALDKDP CSVLPSDYDL FINLSRHSIP RDKSLFWENS HLLVNSFADN TRRFMPLSDV LYGRVADFLS WCRQKNDSGL DYQSCPTSED CENNPVDSFW KRASIQYSKD SSGVIHVMLN GSEPTGAYPI KGFFADYEIP NLQKEKITRI EIWVMHEIGG PNVESCGEGS MKVLEKRLKD MGFQYSCIND YRPVKLLQCV DHSTHPDCAL KSAAAATQRK AHHHHHH Endotoxin: <1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.