SREBF1, GST-Tag, Recombinant (SREBP1, bHLHd1, SREBP-1c, Sterol Regulatory Element-Binding Protein 1)
Catalog No : USB-501019
482.77€
0.00€
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| Product name | SREBF1, GST-Tag, Recombinant (SREBP1, bHLHd1, SREBP-1c, Sterol Regulatory Element-Binding Protein 1) | ||
|---|---|---|---|
| Catalog No | USB-501019 | ||
| Supplier’s Catalog No | 501019 | ||
| Supplier | US Biologicals | ||
| Source antigen | E. coli, Recombinant | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 37 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Lysate | ||
| Purity | Lysate | ||
| Form | Supplied as a lyophilized powder. Reconstitute with 200ul sterile dH2O. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Lysate | ||
| Description | This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. Source: Partial length protein corresponding to of SREBF1, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~37kD Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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