Nanog, Recombinant, Human (Homeobox Transcription Factor Nanog)
Catalog No : USB-220086
457.48€
0.00€
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| Product name | Nanog, Recombinant, Human (Homeobox Transcription Factor Nanog) | ||
|---|---|---|---|
| Catalog No | USB-220086 | ||
| Supplier’s Catalog No | 220086 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 34.7 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~98% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in 10mM acetic acid. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~98% (SDS-PAGE) | ||
| Description | Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self-renewal via a STAT3 independent pathway. Recombinant human Nanog is synthesized as a 304aa polypeptide lacking a signal sequence for secretion. Source: Recombinant protein corresponding to 304aa from human Nanog, expressed in E. coli. Molecular Weight: ~34.7kD Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDV Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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