Notch1, Recombinant, Mouse,Fc (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300)
Catalog No : USB-045099
529.90€
0.00€
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| Product name | Notch1, Recombinant, Mouse,Fc (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300) | ||
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| Catalog No | USB-045099 | ||
| Supplier’s Catalog No | 045099 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human, Mouse, CHO cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 85 | ||
| Storage | 4°C/-20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS. Reconstitute with 50ul sterile ddH2O. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥95% (SDS-PAGE) | ||
| Description | Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. Sequence: The extracellular domain of mouse Notch1 (aa19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1, expressed in CHO cells. Molecular Weight: ~85kD (SDS-PAGE) Endotoxin: <0.1EU/ug (LAL test; Lonza). Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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