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Categories: Peptides & Proteins / Proteins

Product name			Notch2, Recombinant, Mouse,Fc (Neurogenic Locus Notch Homolog Protein 2, Motch B)
Catalog No			USB-045102
Supplier’s Catalog No			045102
Supplier			US Biologicals
Source antigen			Recombinant, Human, Mouse, CHO cells
Reactivity
Cross reactivity
Applications
Molecular weight			87

Storage			4°C/-20°C
Other names
Grade			Highly Purified
Purity			≥95% (SDS-PAGE)
Form			Supplied as a lyophilized powder in PBS. Reconstitute with 50ul sterile ddH2O.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥95% (SDS-PAGE)
Description			Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. Sequence: The extracellular domain of mouse Notch2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4°C Long-term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.