RNF4, Recombinant, Human, aa1-190, His-Tag (E3 Ubiquitin Ligase RNF4, RES4-26, SLX5, SNURF)

Catalog No : USB-138730
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Product name RNF4, Recombinant, Human, aa1-190, His-Tag (E3 Ubiquitin Ligase RNF4, RES4-26, SLX5, SNURF)
Catalog No USB-138730
Supplier’s Catalog No 138730
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 23.7
Storage -20°C
Other names
Grade Highly Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in 20mM tris-HCl buffer, pH 8.5, 0.2M sodium chloride,1mM DTT, 30% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description E3 ubiquitin ligase RNF4, also known as RNF4, contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Source: Recombinant protein corresponding to aa1-190 from human RNF4 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~23.7kD (213aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGS VIVDERRRPR RNARRLPQDH ADSCVVSSDD EELSRDRDVY VTTHTPRNAR DEGATGLRPS GTVSCPICMD GYSEIVQNGR LIVSTECGHV MSTRKRR GGAINSRQAQ KRTREATSTP EISLEAEPIE LVETAGDEIV DLTCESLEPV VVDLTHNDSV FCSQCLRDSL KNANTCPTCR KKINHKRYHP IYI Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.