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Categories: Peptides & Proteins / Proteins

Product name			ZNF346, Recombinant, Human, aa1-294, His-Tag (Zinc finger protein 346)
Catalog No			USB-350397
Supplier’s Catalog No			350397
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			35.3

Storage			-20°C
Other names
Grade			Purified
Purity			>90% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl (pH 8.0), containing 0.2M sodium chloride, 2mM DTT and 50% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>90% (SDS-PAGE)
Description			ZNF346 is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. ZNF346 may be involved in cell growth and survival. Description: E. coli-expressed recombinant protein corresponding to aa1-294 of human ZNF346, fused to a His-tag at the N-terminus. Molecular Weight: ~35.3kD (confirmed by MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEYPAPA TVQAADGGAA GPYSSSELLE GQEPDGVRFD RERARRLWEA VSGAQPVGRE EVEHMIQKNQ CLFTNTQCKV CCALLISESQ KLAHYQSKKH ANKVKRYLAI HGMETLKGET KKLDSDQKSS RSKDKNQCCP ICNMTFSSPV VAQSHYLGKT HAKNLKLKQQ STKVEALHQN REMIDPDKFC SLCHATFNDP VMAQQHYVGK KHRKQETKLK LMARYGRLAD PAVTDFPAGK GYPCKTCKIV LNSIEQYQAH VSGFKHKNQS PKTVASSLGQ IPMQRQPIQK DSTTLED Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C or lower. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.